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Cancer Research: Diabetes and pancreatic cancer.


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Diabetes and pancreatic cancer.

Minerva Gastroenterol Dietol. 2012 Dec;58(4):331-45

Authors: Muniraj T, Chari ST

Abstract
The relationship between diabetes and pancreatic cancer is complex. Diabetes or impaired glucose tolerance is present in more than 2/3rd of pancreatic cancer patients. Epidemiological studies have consistently shown a modest increase in the risk of pancreatic cancer in type 2 diabetes, with an inverse relationship to duration of disease. Additionally, recent studies suggest that anti-diabetic medications may modulate the risk of pancreatic cancer in type 2 diabetes. Subjects >50 years of age with new onset diabetes are at higher risk of having pancreatic cancer. However, to screen new-onset diabetes for pancreatic cancer, additional markers are needed that can distinguish pancreatic cancer-associated diabetes from type 2 diabetes.

PMID: 23207610 [PubMed - indexed for MEDLINE]

pubmed: clinical cancer rese…

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